WDR38, A NOVEL EQUATORIAL SEGMENT PROTEIN, INTERACTS WITH THE GTPASE PROTEIN RAB19 AND GOLGI PROTEIN GM130 TO PLAY ROLES IN ACROSOME BIOGENESIS

WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis

The WD40-repeat containing (WDR) proteins are enriched in the testis and play important roles in spermatogenesis.In the present study, we investigate the expression profile of WDR38, a novel member of the WDR protein family, in humans and mice.RT-qPCR (reverse transcription-quantitative polymerase chain reaction) results demonstrate that WDR38 mRNA

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The coefficient of determination R-squared is more informative than SMAPE, MAE, MAPE, MSE and RMSE in regression analysis evaluation

Regression analysis makes up a large part of supervised machine learning, and consists of the prediction of a continuous independent target from a set of other predictor variables.The difference between binary classification and regression is in the target range: in binary classification, the target can have only two values (usually encoded as 0 an

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Large-scale brain functional network topology disruptions underlie symptom heterogeneity in children with attention-deficit/hyperactivity disorder

Accumulating evidence suggests brain network dysfunction in attention-deficit/hyperactivity disorder (ADHD).Whether large-scale brain network connectivity patterns reflect clinical heterogeneity in ADHD remains to be fully understood.This study aimed to characterize the differential within- and between-network functional connectivity (FC) changes i

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MD SIMULATION STUDIES TO INVESTIGATE ISO-ENERGETIC CONFORMATIONAL BEHAVIOUR OF MODIFIED NUCLEOSIDES M2G AND M22G PRESENT IN tRNA

Modified nucleic acid bases are most commonly found in tRNA.These may contain modifications from simple methylation to addition of bulky groups.Methylation of the four canonical nucleotide bases at a wide variety of positions is particularly prominent among the read more known modification.Methylation of N2 group of guanine is a relatively common m

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